Poison Detection in Human Organs

Poison ivy, poison oak, and poison sumac.

Immunological detection of microtubule poison-induced conformational changes in tubulin.

The interaction of tubulin-microtubule poison complexes with anti-tubulin antisera has been investigated using radioimmunoassay. The binding of the major antiserum used in this study to tubulin does not interfere with the binding of colchicine to the tubulin or affect the decay of the colchicine-binding activity of the tubulin. Conversely, if colchicine is incubated with the tubulin, forming tu...

Searching for a Poison in a Poison

chlorinated biphenyl (PC8I mixtures had been described previously. High mortality, liver damage, and edema were associated with only two of the three PCB5. Using column and gas chromatography, several compounds were identified in the diethylether fracdon of these two PCBs. A chick embryo assay confirmed the high toxicity of this fraction. Mass spectremetric and microcoulometric analyses indicat...

Poison Romance and Poison Mysteries

Selenium in human male reproductive organs.

The objective of the study was to obtain information on the concentration and distribution of selenium throughout the human male reproductive tract. Material was removed at autopsy from 41 men who had died suddenly and unexpectedly. Semen samples were also provided from 184 men attending an andrology clinic for fertility investigation and from 32 healthy volunteers. Significant positive correla...